CASE REPORT
Year : 2012  |  Volume : 4  |  Issue : 1  |  Page : 64-69

Mucous membrane pemphigoid with exclusive gingival involvement: Report of a case and review of literature


1 Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, India
2 Department of Oral Medicine and Radiology, Z.A Dental College and Hospitals, A.M.U, Aligarh, Uttar Pradesh, India

Correspondence Address:
Shamimul Hasan
C/O Mr. Mohd. Javed Khan, C-4, Duplex Quarters (New), Sir Syed Nagar, Aligarh - 202 002, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-8844.99884

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According to Sir William Osler, Mouth is the mirror of the body which reflects systemic ­diseases. The oral mucosa may be affected by a variety of mucocutaneous diseases and oral lesions may occur first or very early in several mucocutaneous disorders. The erosive gingival lesions associated with vesiculobullous diseases such as lichen planus, cicatricial pemphigoid, and pemphigus vulgaris have been collectively referred to as "Desquamative gingivitis" (DG). Gingival desquamation is a clinical sign in which the gingiva appears reddish, painful, glazed and friable with destruction of the epithelium. This gingival desquamation is due to various disease processes in gingiva. The disease process may be a localized disease of gingiva or a systemic disease which manifests in the gingiva. It is important to be aware of this rare clinical entity so as to distinguish DG from plaque induced gingivitis which is an extremely common condition, easily recognized and treated daily by the dental surgeon. Accurate diagnosis and effective treatment of these lesions may greatly diminish or reverse disease progression. Here by, we present a case of mucous membrane pemphigoid presenting as gingival desquamation in a 45 year old female. Our patient presented with generalized erythematous gingiva and gingival desquamation involving the free, attached and marginal gingiva of left maxillary and mandibular dentition. However, other mucosal and skin involvement was not appreciated in the present case. Thorough history, clinical examination, histopathology and immunofluorescence studies helped us to arrive at the diagnosis of this rare sub-epithelial blistering disorder.


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