Year : 2012  |  Volume : 4  |  Issue : 1  |  Page : 20-25

Biological role of lectins: A review

1 Department of Oral Pathology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India
2 Department of Oral Pathology, Lenora Institute of Dental Sciences, Rajamandry, Andhra Pradesh, India

Correspondence Address:
K Kiran Kumar
Department of Oral Pathology, SIBAR Institute of Dental Sciences, Guntur, Andra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0975-8844.99883

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Lectins comprise a stracturally vary diverse class of proteins charecterized by their ability to selectively bind carbohydrate moieties of the glycoproteins of the cell surface. Lectins may be derived from plants, microbial or animal sources and may be soluble or membrane bound. Lectins is a tetramer made up of four nearly identical subunits. In human, lectins have been reported to cause food poisoning, hemolytic anemia, jaundice, digestive distress, protein and carbohydrate malabsorption and type I allergies. The present review focuses on the classification, structures, biological significance and application of lectins.

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